DPCstruct | MC40686

Metacluster Properties and Pfam Annotations

Number of structural domains2587
Mean domain length (aa)226 ± 46 aa
Standard deviation of domain lengths46.49
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.76
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.81
Pfam Score79.42
Assigned Pfam label(s) PF01594- CL0020- CL0398- CL0263- CL0396

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445FZ75 52-278 None
A0A7S4QGM1 96-263 None
A0A2P6N293 397-613 None
A0A3L8T0C5 52-205 None
A0A7X8LTQ4 7-232 None
A0A7X8QWY0 66-260 None
A0A8A9E7H5 61-310 None
E2CQ22 16-255 None
A0A498G7C4 13-222 None
A0A087HRP5 557-827 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.