DPCstruct | MC40686

Metacluster Properties and Pfam Annotations

Number of structural domains2587
Mean domain length (aa)226 ± 46 aa
Standard deviation of domain lengths46.49
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.76
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.81
Pfam Score79.42
Assigned Pfam label(s) PF01594- CL0020- CL0398- CL0263- CL0396

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V5NSJ2 8-246 GSGSQGNAAVIGFGQRRFLLDAGLSCRRIVQGLEALGITLDDLNGLFITHDHEDHVKGLRVLLGKREELPIFATRGTLAAIERKGLE…
A0A6B7PW49 207-432 YPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDR…
A9WVD1 30-201 None
A0A0D8XEE0 22-242 None
A0A7G7JKC1 278-534 None
A0A0G4HCE0 17-225 None
M1UXY6 302-574 None
A0A7C0ZNP2 1-207 None
A0A7C2CWV6 7-156 None
A0A0P7GPV6 21-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.