DPCstruct | MC40680

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)280 ± 38 aa
Standard deviation of domain lengths37.56
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score79.55
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)27.02
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S6XA57 53-357 TAPLTVRNELTKAIPMIWRCIFRALEPTRIVIHANHSDLLLVIGRVLTPFGEPTIPSLEDLHILELDRKQSSVVADSADHDSTDYGL…
A0A177C6X7 99-370 RHVSTADAPLAHAVREIWDQVFSNLDPNRVVVAAPPSTLSALLDSQMLSSDAWAFDMKMHYVEFLQQDPQRAAHRNPECRPWGNALV…
A0A370TUA2 501-737 None
A0A6A5WYS9 178-467 None
A0A1L9VNM6 1-308 None
A0A4S9CNT0 35-342 None
A0A395ILL2 15-264 None
A0A2P7YIX7 67-305 None
A0A086T9B3 95-395 None
C4JKV7 220-497 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.