DPCstruct | MC40676

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)386 ± 66 aa
Standard deviation of domain lengths66.26
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.79
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)32.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S6X5S3 8-452 KNGKPKTDIEAAASTETAPSTATTAAPLAAPWTATSTGPSSVPVTFPSTVPSSPKASSFADSDRTGKTGRSLFFEELKYEVMCNYIF…
A0A4Y8DG37 89-401 GVMVRKDRTEYLCRPPALASSTFGRAMKIMNVSAAMTINSTVVQPFLTRSPDALDVPLTNGLRVQILPTLEDLPRARRAHYAAFIAR…
A0A163FIR5 262-703 None
A0A179F2Y4 1-500 None
A0A4S9C599 1-441 None
A0A0E9NQB9 34-495 None
M2Q872 31-378 None
A0A395J675 1-322 None
A0A0G4MKN0 136-585 None
A0A139HB84 8-323 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.