DPCstruct | MC40657

Metacluster Properties and Pfam Annotations

Number of structural domains159
Mean domain length (aa)137 ± 16 aa
Standard deviation of domain lengths15.97
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score84.47
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.93
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A535ZB73 4-123 EIRLELFETAVSRLLSEGEDRDCVIFELRGRPDCYVQFILHDGALLGEVGSRGWAPEGELLDRERITALGCLGFEGGGHRANFARDH…
A0A7D6Z1B4 39-167 GAAVTDWGNFTARLTLMLTAMCDSDWIVLEADGGRFARFGVGFSRDILCEIASNDDLDERYRMSSDDEAAMGKLGWKAGKYSWELYL…
A0A117N948 142-269 None
A0A1M7RCQ1 151-309 None
A0A2G2LAH6 206-330 None
A0A517Y4K3 1-126 None
A0A662V707 4-139 None
A0A449GXH5 5-133 None
A0A1V5ZME3 1-132 None
A0A7K0C4H3 2-132 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.