DPCstruct | MC40611

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)140 ± 9 aa
Standard deviation of domain lengths8.75
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score91.37
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)37.38
Pfam Score100.00
Assigned Pfam label(s) CL0268

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z1I7J3 15-141 ENGSGGWLSDSTFVGGMFGAYFGNQQFTSRNLAFYGCKTALQISWDWAWTMQGINIKNCGSGIDVVGEAGGSLGTSKNVRSLTLLYL…
A8Q103 1-138 MENASGGFMSDLTFHGGRFGAWMGNQQFTVRNVYFSECKTAICMHWNWAWTFIDVHVHNCEIGLELLGMFPDKQGVGSLILSDWDVS…
A0A2S4L0D2 429-548 None
A0A1Z5SVZ4 4-144 None
J3PE45 202-343 None
U7PQ26 723-861 None
U7Q190 374-514 None
A0A0C9UMK5 224-365 None
A0A2P6MUI7 571-712 None
A0A194X730 163-308 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.