DPCstruct | MC40609

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)118 ± 4 aa
Standard deviation of domain lengths4.30
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score91.86
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)31.01
Pfam Score100.00
Assigned Pfam label(s) CL0323

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E3S715 320-438 DTISSEETEWLKKRRANTIDPMRQFLERVNIQGFNVGQYIDKHRSNTSALPNIAISFSGGGYRALLNGAGALSAFDSRTSNSTSAGH…
A0A0D2AIM9 467-588 PAKGLSFQEEAWVRGRKSVVLDAFSAYLQRVNITGLDVPALVNAMKSHNNSGVPVISMAISGGGWLSANTGVGVLRAFDARFPDAID…
Q6C150 42-154 None
A0A316YCL0 47-163 None
A0A2V8ZRQ2 8-118 None
A0A1E4TX49 81-200 None
A0A2V5SWR4 4-123 None
A0A397GWD4 653-777 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.