DPCstruct | MC40600

Metacluster Properties and Pfam Annotations

Number of structural domains189
Mean domain length (aa)214 ± 45 aa
Standard deviation of domain lengths45.25
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.62
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)22.75
Pfam Score100.00
Assigned Pfam label(s) PF14240

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E4ZUL3 15-225 TVTKEHIVMKSKNLPNHPTANFPDYERKLDGNPNYVAEQNLTFYLPLVPKKNPRPVAMDKRNTNRALPGGPIGVAANGVIFFNPFDH…
A0A7K0ZIQ3 34-224 GFSAFSSSVKTLKSGKYYLVESNGLPPHNMMVGITNWQQQVPVPQPYSGSNAWQIPTTPKLAATPLSAKNNLFRGAIALAADGVPIF…
A0A2U2X9U1 2-219 None
A0A3N4SBU1 229-390 None
A0A349JWF5 559-748 None
A0A6P4YX58 26-239 None
A0A1J5T9G0 109-395 None
A0A2E9J422 104-398 None
A0A6U2AEM6 87-321 None
A0A222FHV2 120-427 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.