DPCstruct | MC40590

Metacluster Properties and Pfam Annotations

Number of structural domains102
Mean domain length (aa)192 ± 31 aa
Standard deviation of domain lengths31.29
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score88.68
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)24.06
Pfam Score94.51
Assigned Pfam label(s) CL0245- PF02734

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U0VQW4 412-624 GPRPSDPKLFLAALESALKSVIAAEPEITRYDTIAGDGDAGLTLKAGAQGILDAISENRIPDDDVVAAMVACSEVVEREMGGTSGGL…
F3WH81 4-148 GFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQATQARQILTLEELYQMFRDGADGVISRGKAEPGDKTMC…
A0A811MW39 172-341 None
F6FQ17 5-230 None
A0A482VFX5 352-521 None
A0A5D0PS61 1-198 None
A0A848A030 5-128 None
A0A377YXK9 5-149 None
A0A7S2UN07 95-303 None
A0A6L8NDH6 2-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.