DPCstruct | MC40581

Metacluster Properties and Pfam Annotations

Number of structural domains601
Mean domain length (aa)123 ± 19 aa
Standard deviation of domain lengths19.13
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.96
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)28.23
Pfam Score97.86
Assigned Pfam label(s) CL0213- PF00057- PF01186- CL0550- CL0154

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W2GIV8 190-313 None
A0A0S4JH04 297-460 None
A0A7M7GHV0 142-247 None
A0A7M7N9M4 115-233 None
A0A7M7HFZ4 111-227 None
A0A7M7HIR8 70-190 None
A0A7M7HN35 1-100 None
A0A7M7N006 18-140 None
A0A7M7N5H2 2-112 None
A0A7M7N5Q6 28-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.