DPCstruct | MC40581

Metacluster Properties and Pfam Annotations

Number of structural domains601
Mean domain length (aa)123 ± 19 aa
Standard deviation of domain lengths19.13
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.96
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)28.23
Pfam Score97.86
Assigned Pfam label(s) CL0213- PF00057- PF01186- CL0550- CL0154

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J6BE83 25-148 LFDVQKKGPPQEGGLRLVGGDLPNKGRVEVYHDGQWGTVCDDDWDLNEARVVCQQLGFPGAVSAIPGGTYGEGSGPIWLDNMNCKGS…
A0A1S3HLM0 91-194 TGRIRLVNGSHSREGRIEVFYKGQWGTVCDDRFDVKDARVVCRQLGYPTAYPTVYASARFGQGTDPIWLDDLDCVGSELDIKSCANR…
A0A2B4SUN2 16-135 None
A0A7S4P8Y3 197-320 None
A0A668S800 21-87 None
A0A6S7FTR4 283-389 None
C3ZI36 733-858 None
K7F578 260-373 None
A0A6P8H0T6 113-238 None
A0A6P8HKM8 73-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.