DPCstruct | MC40578

Metacluster Properties and Pfam Annotations

Number of structural domains857
Mean domain length (aa)123 ± 22 aa
Standard deviation of domain lengths21.58
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.31
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.11
Pfam Score95.72
Assigned Pfam label(s) CL0228- PF03094- CL0046- CL0030- CL0487

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U3KGY6 144-271 None
A0A4R5P217 27-174 None
A0A2P8VQB0 908-1026 None
A0A250WPZ4 28-143 None
A0A7C9CGR4 358-487 None
A0A7C9CMZ3 202-312 None
A0A452Z9E7 1-85 None
A0A2G8JMG7 38-143 None
A0A7J2LKG7 476-589 None
A0A1D5P3I6 459-584 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.