DPCstruct | MC40578

Metacluster Properties and Pfam Annotations

Number of structural domains857
Mean domain length (aa)123 ± 22 aa
Standard deviation of domain lengths21.58
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.31
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.11
Pfam Score95.72
Assigned Pfam label(s) CL0228- PF03094- CL0046- CL0030- CL0487

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y7JDF2 9-117 None
A0A812R9Y8 358-503 None
A0A438E3F6 249-377 None
A0A3Q0FBN3 16-133 None
A0A7R9ZR38 2-122 None
A0A251XUJ1 575-718 None
A0A287I3X1 385-521 None
A0A1H6K5I0 138-286 None
A0A2A2KBW4 45-170 None
M8ASC4 404-563 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.