DPCstruct | MC40578

Metacluster Properties and Pfam Annotations

Number of structural domains857
Mean domain length (aa)123 ± 22 aa
Standard deviation of domain lengths21.58
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.31
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.11
Pfam Score95.72
Assigned Pfam label(s) CL0228- PF03094- CL0046- CL0030- CL0487

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A358D3V5 48-163 AIPSVSAVGTDLEVEDLLVGDGEAVEPGDTVSVHYLGSLVDGTVFDTSWSRGRPFTTQIGVGMVIQGWDQGIIGMREGGRRLLKVPS…
A0A7I7KPA0 64-178 RVTVTAPFSVSQTQVHTLRAGDGPVVSSTANVSVCYMGVNGRDGSVFDSSYERGAPVDFPLTGVVPGFQKAIAGQKVGSTVAVAMVP…
A0A0D2NVZ5 396-529 None
A0A504X728 140-261 None
A0A2G8L6I5 2-106 None
A0A521FRK1 480-597 None
K8FCB0 23-152 None
A0A7S4E3P2 4-98 None
A0A034VLD7 873-996 None
A0A1Q9C363 3-113 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.