DPCstruct | MC40513

Metacluster Properties and Pfam Annotations

Number of structural domains72
Mean domain length (aa)108 ± 19 aa
Standard deviation of domain lengths18.51
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.42
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)21.51
Pfam Score100.00
Assigned Pfam label(s) CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2V3B1 193-291 VSSSSDMKFKLNTEGDPKQYSNPEGDISIAPSLVYHNNNITVFRFDNVDPDELPQIFRVLEDLTEERLKMVWLGDLVAVNGVHDVLS…
U4X157 210-303 PVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIKDK…
D3SGS2 31-132 None
A0A381A4G6 22-126 None
K2KRG8 5-84 None
D3SGS3 10-116 None
A0A1Q6UDE1 185-349 None
A0A1V1PA41 239-356 None
A0A838L1S1 94-195 None
A0A4R0NTP8 56-157 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.