DPCstruct | MC4046

Metacluster Properties and Pfam Annotations

Number of structural domains124
Mean domain length (aa)128 ± 26 aa
Standard deviation of domain lengths26.45
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score87.13
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)28.05
Pfam Score98.59
Assigned Pfam label(s) CL0286- PF02807

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P4YVF8 127-265 TGRSIRGISLPPHCSRAERRAVETISLDALSHLTGEFAGKYYPLSGMTDAEQEQLIADHFLFDKPVSPLLTCAGMARDWPDARGIWH…
A0A7S0FWZ2 377-503 HLKASWDLQGLRAAGKMCADERCEAERVITNALSELTGSLEGEYLPLATSTSYPARPGGMSEMERQVLNAHGLLLQANGASGRGVFV…
A0A553N4L7 181-266 None
A0A1D2MVW0 344-466 None
A0A7S4PGS4 164-301 None
A0A6P8HWY1 145-274 None
A0A2G8LKB0 191-309 None
T1GFR8 17-134 None
A0A1Q9C880 74-228 None
A0A086KW13 107-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.