DPCstruct | MC40443

Metacluster Properties and Pfam Annotations

Number of structural domains652
Mean domain length (aa)205 ± 52 aa
Standard deviation of domain lengths51.81
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.85
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)11.17
Pfam Score76.48
Assigned Pfam label(s) CL0023- PF16322- CL0063- CL0395- PF20236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3M7RPA5 16-242 None
A0A446LGQ8 6-163 None
A0A812ST80 159-357 None
L1ILT3 113-296 None
L1IPN8 43-237 None
L1IQK0 26-242 None
A0A817JJL0 76-257 None
A0A812XI01 364-587 None
A0A812Z0V0 79-283 None
A0A1S8A569 439-722 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.