DPCstruct | MC40386

Metacluster Properties and Pfam Annotations

Number of structural domains817
Mean domain length (aa)108 ± 18 aa
Standard deviation of domain lengths17.86
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score84.92
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)16.93
Pfam Score61.89
Assigned Pfam label(s) CL0023- PF11987- CL0526- CL0740- CL0437

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A542ZXE8 97-202 TAVTPRTVPAATGSTDGGSAHGFSLPVDDAFTIAGRGTVVTGTVASGQVRGGQSVTLHRGPAALGTYRITGIEAFRKRLDTASAGDT…
A0A6J1BMD8 1-119 EAVFPCVLKILPNCIFNKKDPIVLGVDVLEGIARVGTPICIPQREFIDIGRIASVENNHKPVDVAKKGQKVAIKIVGSNPEEQQKMY…
A0A401FI79 129-221 None
A0A1E3C1M3 45-144 None
A0A5E7QRD8 381-472 None
L5JNJ0 79-188 None
A0A378B6Z4 2-97 None
A0A2D0Q7Y8 277-374 None
A0A7S0VU48 23-129 None
A0A351YC71 550-642 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.