DPCstruct | MC40382

Metacluster Properties and Pfam Annotations

Number of structural domains57
Mean domain length (aa)197 ± 31 aa
Standard deviation of domain lengths31.31
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score75.89
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)21.50
Pfam Score100.00
Assigned Pfam label(s) CL0187

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H2B1X1 2-194 MTHEGFAYWDGDLPTDLADDLFTALVAIFEVASGSEINQIYKLSDSGYVFGVFSGIQVDSSITNMLTILSTPIVDENGINNYFYLES…
Q707V6 11-205 TLVSSQNIMFGYTGGDKIDIHKKQALASISEFKSLLNNFDQRQSFKYQKDDIAAFVWSGSMVDNKDFSSNLISVLTDEVNEYGIPDE…
A0A2S4LAS4 113-331 None
A0A318YKJ9 39-214 None
A0A162LXD7 164-400 None
A0A6A5V0T5 1-200 None
A0A1B8EWV0 87-308 None
H2AUW5 24-213 None
A0A5N6XCF2 100-260 None
A0A0A2JFC6 329-526 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.