DPCstruct | MC40324

Metacluster Properties and Pfam Annotations

Number of structural domains338
Mean domain length (aa)256 ± 45 aa
Standard deviation of domain lengths45.33
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.03
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)13.26
Pfam Score47.68
Assigned Pfam label(s) CL0369- CL0287- PF20597- PF11999

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V6AIM3 23-268 RANADVADVVPQLGDLERWTTFSLGSGNRPSLAVGHLFIDGDLGFAGAGNFLIGGHSNVAGDVYVPSNGTVLAIDHAVFTGSIFDNQ…
A0A2N1UPR3 2-172 DASNTFAKSPMVTGRIYAANLTPPTPTKMTTAIGDLATAYTDAAGRAIPDFAELGTGQIGGLTLVPGLYKWGTNVLISTDVTLNGGP…
A0A1F3IW73 69-294 None
A0A0B8NYT5 2-294 None
A0A416IC67 19-241 None
A0A535A6S0 3-311 None
A0A7U4E8G8 78-371 None
A0A7C4LWP1 122-416 None
A0A1X7NRP6 95-316 None
A0A1G1AH90 154-382 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.