DPCstruct | MC40312

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)110 ± 17 aa
Standard deviation of domain lengths16.61
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.20
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)20.61
Pfam Score91.67
Assigned Pfam label(s) PF11535- PF13817

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C6VVN0 8-118 AEREHRIEMEIVVDAYTEEERAMSWYCYLEEQLSFPFKASVRKPMDSSPLPTGEHVCVTGLAHEDLCRVGIFVWVRWKERDVVAPLA…
F4F8D1 2-91 IEEATVDAYGDDEQLTGLFTMIEEHLAVPFTTTVLGVEVTVRKIDLTADTIVALCARGHHRQRIGLLDLPLPTPPPDGAGWIDAYRH…
A0A1F8V793 6-108 None
A0A536ZSP1 14-108 None
U3UAI2 95-193 None
A0A2M7QXK4 148-255 None
A0A7C2Y7X1 23-144 None
A0A849T467 15-132 None
A0A8A9EUH8 233-358 None
A0A7C7QSX1 238-339 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.