DPCstruct | MC40296

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)205 ± 26 aa
Standard deviation of domain lengths25.79
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.18
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)22.03
Pfam Score75.74
Assigned Pfam label(s) PF19295- PF01458

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6N3UFV0 5-190 QQTALELAAEQQTPAWLAALRQQGASTWAAAAWPGRKTEHWKYISLAPLQQCEQLGWSSESDDVALDAVEQIELDAIRLVFVNGRFN…
A0A447KZY4 11-208 RALQTLYSLFEAHGGEQSAYALAHWQQALRLGWPTRKHENWKYTPLEGLLERQFVAPIVSDITAAQRDALALDIDAYRLVFVDGRYS…
A0A535T5Z3 6-218 None
A0A0R0HCK9 3-269 None
W4SH11 198-406 None
A0A178IIA4 127-372 None
A0A381GMS1 9-189 None
A0A1F2P3X3 3-166 None
A0A1B0C170 29-237 None
A0A2U1QG26 220-436 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.