DPCstruct | MC40214

Metacluster Properties and Pfam Annotations

Number of structural domains160
Mean domain length (aa)136 ± 21 aa
Standard deviation of domain lengths20.98
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score77.83
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)29.80
Pfam Score81.92
Assigned Pfam label(s) CL0255- PF03946- PF00298- PF00687- CL0039

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U6UJT3 12-149 RKPVLATIRLIVPAGAARPAPPVGPVLGFHRLNLMAFCKDFNARTQKYKAMQVTLTDYKDSTFEFVVKSPSVSWFLKKAAGIETASI…
Q4DTS8 40-207 AVPEFPGKRVLHNWRFFIKAGKAATGPPVGQEFSKLGLKAMDFAKSFNDRTKPHFKDDVELIVRIQVYFDKSYLYTIEPPPTAWFIL…
A0A7R8XJC8 139-252 None
A0A0G0V2B9 7-100 None
A0A5N6P7U5 342-500 None
A0A7J9KH35 37-180 None
A0A7J6KWC3 223-380 None
A0A7T5Y820 8-140 None
A0A836AUD4 1-97 None
A0A0B7MZ25 221-378 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.