DPCstruct | MC40204

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)136 ± 26 aa
Standard deviation of domain lengths25.97
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score94.43
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)59.38
Pfam Score100.00
Assigned Pfam label(s) PF00384

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378B0J9 155-299 MIIVGAGLNHWFHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV…
A0A377CWI7 1-150 MIILGAGVNHWYHMDMNYRGMINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHSSQWRYEKV…
A0A2X3CFL2 155-289 None
W4TWP0 361-466 None
A0A7K0F4M0 1-109 None
A0A378F4Z1 70-238 None
A0A380FN20 181-304 None
A0A0D1IB09 292-462 None
A0A2Z5QRI8 129-273 None
A0A376KUC0 105-273 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.