DPCstruct | MC40184

Metacluster Properties and Pfam Annotations

Number of structural domains250
Mean domain length (aa)188 ± 36 aa
Standard deviation of domain lengths35.61
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score78.56
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)25.91
Pfam Score98.95
Assigned Pfam label(s) CL0063- CL0016- PF00067- CL0214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J6PQF3 231-437 STALPAFAAYKAVEWYAESSPKSLRPSPDQASLLYESLHEKYSPVVRNATVALRGFYLKASQMMSLRDEFLPKQYLEWCRKMQDQAP…
A0A842X6Y2 9-194 RAHKRKIYISVLRFLLIIRKIHRYSKKGRSEKVRKLAEKNVEIFYRLGPTFIKFGQVLSSRGDMFPQEYIDKMSELQDIVPPAPFEE…
A0A2J8AIE6 138-350 None
A0A849WRD7 240-475 None
A0A1R3ICB4 379-612 None
A7B2B3 30-139 None
A0A5P1EVL4 10-107 None
A0A498KUN5 264-495 None
A0A7V9TYG3 12-195 None
A0A4V5NB75 163-367 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.