DPCstruct | MC40182

Metacluster Properties and Pfam Annotations

Number of structural domains265
Mean domain length (aa)236 ± 53 aa
Standard deviation of domain lengths52.96
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score75.18
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)16.22
Pfam Score90.66
Assigned Pfam label(s) PF20845- PF16566- CL0123- CL0020- PF12350

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H2AMW6 2-250 None
A0A1Y1UXR7 4-313 None
A0A4S4DHV9 129-478 None
A0A553N5T0 10-186 None
A0A7J7M325 1-133 None
A0A6A4VR49 86-395 None
A0A6P6U1M1 30-295 None
A0A0V0XV64 1-191 None
A0A2G5BHV5 3-221 None
A0A812U5R9 121-391 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.