DPCstruct | MC40182

Metacluster Properties and Pfam Annotations

Number of structural domains265
Mean domain length (aa)236 ± 53 aa
Standard deviation of domain lengths52.96
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score75.18
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)16.22
Pfam Score90.66
Assigned Pfam label(s) PF20845- PF16566- CL0123- CL0020- PF12350

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J6PLE0 14-283 KRSLTEQQVRALDHLRKKLREVAGTQEAIVGVAKIIGDMPSLSAEVCQILAEEHAHSRHINHKLSIFYVFNEIVQRSRTGNQSLLQA…
A0A090M5S3 6-151 TKLSPEDRKSLEEILRHVTTSRDDVRDAMEFAVERAECAGDVVDVIASSLIEPDASLGTVIARLYVVSDILHNASAPVRGVQAYRTE…
A0A1U8F3M0 135-398 None
A0A1A8H7Z7 4-217 None
A0A2H3BLK8 164-593 None
A0A1E3K5H4 2-237 None
K3WU63 1-270 None
M1VK36 13-168 None
L5K596 5-239 None
A0A1Y2HEZ7 5-272 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.