DPCstruct | MC40123

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)402 ± 59 aa
Standard deviation of domain lengths59.39
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score74.53
Mean fraction of residues predicted as intrinsically disordered0.61
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.54
Pfam Score100.00
Assigned Pfam label(s) PF11709

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1B5L8W4 8-361 IRIKQVDSIENVTDFASAADHSLSLEKFQELRVAMSIPRSKELRLFSASSKRTDLWPVSVFEEDRDFTDPRGGKEDDDKRWKFRGPW…
A0A5M8Q215 8-400 IRVDAVDSIDHITDFRSSADHVLTLRKWQEMDIPISIPEPPRKPTASSFSQATIGPPRSVFEAQVDNTELTQQNTGIDQQRWKYKGP…
A0A0E9NC19 59-475 None
M5FY59 1-470 None
A0A166GHZ9 2-390 None
A0A137Q3B7 368-855 None
A0A4S4KPS3 15-301 None
A0A1B9GRL0 1-416 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.