DPCstruct | MC40079

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)213 ± 33 aa
Standard deviation of domain lengths32.89
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score76.76
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)16.69
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A259N9A2 56-287 KVFLDRAASLIAKYDIYEQDHMKRGNKALYECMEYTYDYALDVFNSPLKEDILDAMRWRTKNTTGKMPSASTPPMTLIVKYVFGDTD…
A0A191UHB5 10-251 VLSAQSIVEKADALVKQRESFEQNEYARSNQRLYEILAEVLDMYEQASSSKTTLAETVKQLKTKLEASKVRVQTNTLALTLFVRYVF…
A0A2T7SQ90 51-278 None
D6V4B5 46-240 None
F6IKL0 14-191 None
F3L407 38-245 None
A0A1F4I2T2 11-221 None
A0A259PLJ5 13-273 None
A0A2K1G5Z2 99-289 None
C4ZJA7 36-252 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.