DPCstruct | MC4004

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)153 ± 24 aa
Standard deviation of domain lengths23.83
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score75.94
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)46.79
Pfam Score100.00
Assigned Pfam label(s) PF05661

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z5QTQ3 2-127 PIIKKITLGSLRNKLLIILPIGLLLTAVAPWLLPVALVIGGAYLCFEGGEKILERFGGAAHAEEESGPIDEAQIIRQAITTDFVLST…
A0A7G2IXH5 2-161 LGDDLSLNAQQVSGVRANRELPVVWSVAKGSFVNKVILVPLALLISAFIPWAITPLLMVGGAFLCFEGVEKVLHTLEARKHKESPEE…
A0A1W1CKN7 1-188 None
A0A7G3D6V8 2-130 None
X8F6T6 25-145 None
A0A6G3VNB2 2-129 None
A0A6N8FDV4 18-179 None
A0A7W0VQK9 1-186 None
R4YBM1 4-172 None
A0A014DS34 17-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.