DPCstruct | MC4

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)135 ± 13 aa
Standard deviation of domain lengths13.06
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score86.24
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)23.25
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A372JJE4 24-156 CSVQIRVGKLLLTSLNVTQTYGGLIEGGPSKRFNDRLVQRALESASRGEMPVHLVPPVIKLDERRPHDPTEVLPPLRCIGFFHGPPT…
A0A849WD35 3-135 FIELKCGRSVYISDFDYTRTYGGLIEGMPNEKLNNKIIECAMIRMQLIWGKRKTHLIPPKIDTSDPKHPSLPSTQLTAYIVCNDPVN…
A0A8A9EYB4 2-162 None
A0A5C6B888 12-158 None
A0A2Z3HGU4 76-212 None
A0A496WSG5 1-139 None
A0A8B4ZHI9 6-116 None
A0A2U1JKC2 5-126 None
A0A1Q3HMK2 2-129 None
A0A553BDD9 7-127 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.