DPCstruct | MC39973

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)65 ± 3 aa
Standard deviation of domain lengths2.86
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score95.70
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)49.36
Pfam Score100.00
Assigned Pfam label(s) CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R8XNG2 224-288 VGRVDLKNDRQAGVLRVQAAWSEPGAPRDTAERLAGVLRETAAWQGLGAIDVRPRGTLAAALAAE
A0A6I5VGK2 367-431 VARVDLKADRERSTLLVPTVNAEPGTDTKIVAAELKAELRQLAGWLGLERIVVGRAGNLAAALRA
A0A7V9ILR5 179-245 None
A0A2P8AWA3 336-396 None
A0A523DNN0 337-397 None
A0A2S8BJ81 175-241 None
A0A094Q1V6 485-554 None
A8KZV1 304-369 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.