DPCstruct | MC39958

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)205 ± 15 aa
Standard deviation of domain lengths14.77
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score80.98
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)42.72
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0RYP9 1-223 MLDENLPVYFLKPAADGIKHHRDIYLSHHGSSPAPSYALHNTDPASTSPAQKNCYAVALFDAYNPDILFGEVLARPDWTQPTLNQEE…
A0A3L6N8L0 1-191 MLDENLPTYRFKTSSENPLNNILYFTHNGSDPTPEYLIKRPAPSEANGQYALGIFDSQNTSVIYAEVDVKPDWVAPTLSAAEIRAQN…
A0A094GJ53 1-216 None
A0A3N4INF3 1-201 None
A0A0F4YZM2 503-718 None
A0A6A6JSA3 1-220 None
A0A124BXE6 338-555 None
U4LQH5 1-169 None
A0A2W1H7N6 1-208 None
A0A063C7L7 1-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.