DPCstruct | MC39911

Metacluster Properties and Pfam Annotations

Number of structural domains4190
Mean domain length (aa)140 ± 27 aa
Standard deviation of domain lengths26.70
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.19
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)11.12
Pfam Score79.49
Assigned Pfam label(s) PF05309- PF01327- CL0020- PF19843- PF07382

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3S0EBK1 17-154 VISQSSAQGLDTPEETIAKWRAAVAAADVNAAMTLFAPNASGFATYSRAPISGTSEIRKLYENVLSRLNVPRGNETITISKTMVGES…
A0A3C0E9C5 3-111 EDAWNTREPERVSLAYTVDSVWRNRAEFLSGREMIVQFLRRKWAKELDYRLIKEFWAFDDARISVRFAYEWRDDSGNWFRSYGNENW…
A0A066VAC4 27-201 None
E2C2D4 5-142 None
A0A358SIK2 13-135 None
G8SLB7 162-345 None
G8SC83 110-218 None
A0A810LMU4 2-103 None
A0A6L7GKZ0 109-232 None
A0A7X4L0A7 204-359 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.