DPCstruct | MC3989

Metacluster Properties and Pfam Annotations

Number of structural domains61
Mean domain length (aa)273 ± 48 aa
Standard deviation of domain lengths47.55
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.28
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)25.96
Pfam Score100.00
Assigned Pfam label(s) CL0012

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S7WBE6 2-211 SLYTHEIKTMMYSFGDVRDPLTESASYLEDVVKSNIQHLLNIANGIKIHQKRKSIGIEDICFALRKDPFKVKRIKDCIAYKKYKKNI…
A0A2V5GWQ3 17-327 EDADVESEEQFRDRLTNTWRQMMFVSGETAEPSVETTTLIEEIVRQQVVEILARSTALATRRGVRSISTDDLIFLIRHDKAKVSRLK…
A0A2G8LFV2 65-274 None
A0A1V6TIH5 324-622 None
A0A5J5CRR1 25-239 None
A0A1B7YGP5 13-300 None
A0A2P8ZHT6 20-203 None
A0A0G4MQM8 132-445 None
R8BPX9 135-467 None
A0A1X7TP62 10-246 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.