DPCstruct | MC39888

Metacluster Properties and Pfam Annotations

Number of structural domains128
Mean domain length (aa)146 ± 28 aa
Standard deviation of domain lengths28.10
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.20
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)24.44
Pfam Score65.77
Assigned Pfam label(s) CL0192- CL0144- CL0607- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W5M2S1 2-107 FDENGDPPAAYDIINWQLNKGVVSHVTVGHFDTSPDGGSQLVIDEDSIVWSTGRELPTGVCSESCPPGTRRAARKGQPICCFDCIPC…
L8Y1A2 386-526 LSSEIGTLLELYKIPQLHPFLRKIQFTNGAGDNTSLDDKNNHVTQYDVQNLVRFPDKSWVLVKVGEFFSKSSHNQDLVINEEMIKWP…
A0A061QP75 32-218 None
W5M2Y4 46-207 None
A0A6P6RDR5 212-351 None
A0A061QMY1 150-323 None
A0A2I4CLL0 27-156 None
A0A7R9L4H5 23-152 None
A0A4Z2HJI0 227-426 None
A0A2G8LNN8 101-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.