DPCstruct | MC39699

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)185 ± 28 aa
Standard deviation of domain lengths28.49
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score72.55
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)30.25
Pfam Score100.00
Assigned Pfam label(s) CL0192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S8W661 10-216 LFLRRGVLQFVVIKPALAILIMVLKVFGQYEEGFISWESSYLYLSFAYNISVCWSMYCLVLFYIQCSHDLQPCRPMPKFICVKAIIF…
A0A0D2HW01 160-316 WYRKRWVFIFQYVVVSLGIAVATDITQAINKYCLESSNIHFSHLWLTIIHNISITVAVAACIRFYNALKKDLKHHKPLAKFLSFKLI…
A0A4Q6GDM8 67-253 None
A0A835XRL6 176-355 None
A0A094HD99 131-331 None
A0A842Z9E8 44-210 None
A0A835ALB3 147-301 None
A0A4P1RA51 41-199 None
A0A1X2G9J9 29-220 None
A0A218Z6Y9 4-157 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.