DPCstruct | MC39663

Metacluster Properties and Pfam Annotations

Number of structural domains99
Mean domain length (aa)183 ± 52 aa
Standard deviation of domain lengths52.27
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score91.63
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)20.76
Pfam Score95.83
Assigned Pfam label(s) CL0063- PF00067- CL0475- PF01784

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A853QYK0 6-195 LELYLNNTLETARFKDYCPNGLQVEGRRKIEKIATGVTASVAFLEAALEWGADAVLVHHGYFWRNEAPQITGRKYQRLKLLLANDLN…
A0A7C6BD10 26-204 GKILTKAIKNDIVLYAAHTNIDNAINGVNGILAEKIGLVNLRPLNKGSYLDNENFLGSGAIGELEKPMEKVAFFQHLKETLGLSQIT…
A0A0R2FPC1 8-333 None
A0A6A5SX80 56-292 None
D6E4R1 16-182 None
A0A2E8P6C2 339-583 None
A0A521GHL1 359-483 None
A0A182JW27 553-757 None
A0A645J667 2-112 None
A0A356U768 329-549 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.