DPCstruct | MC39636

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)125 ± 12 aa
Standard deviation of domain lengths12.49
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score78.04
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)22.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A119A3B8 264-382 REQAQAVALQEQRQQTQLRQESQARGQWLLWTGLLLAAILGGFVWHRFIRHRCPSCKSLNFDCTGHKEMDRFKGRIKVHEKNSRGTN…
A0A413SV64 6-133 SLKWILLAAPILNILIVLSGEESVSKWLPSELTFIVVAIGILYFCYGRKSTCPECRKIFALKKTKEEIVGQEDVSVLVETKMRNNRQ…
A0A2M6ZTP1 146-262 None
A0A379MVC8 195-308 None
A0A415S240 526-639 None
A0A0Q8BXM4 108-242 None
A0A417AWM3 346-478 None
A0A2U8FJ22 51-173 None
A0A372UHK5 182-304 None
A0A2E0R145 190-336 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.