DPCstruct | MC39609

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)304 ± 40 aa
Standard deviation of domain lengths40.29
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score74.48
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)18.55
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6V8HGQ6 343-642 RPIGHRPRKPQGTKADDARLRDNPWAVALASPPRYCSATAGRIPKAFLTEMNLVRRIDEATDGKVRQTSMWWMPAALLKDKVPSNTT…
A0A137QGJ0 81-392 FVPQNARHREGEYDKPRQMTEEERKWWSSPYLLIHELQALLLRLAPVRVDESEPATSYKPLPCIITPDGLEHPKFTSRRSIKSVHVI…
A0A397TCM0 18-267 None
A0A165IKG7 90-458 None
H1VGE7 2-245 None
E3Q4K4 8-328 None
A0A0S6X5K3 9-346 None
A0A6G1HW65 1-244 None
W6YQX0 40-367 None
A0A395P0F1 83-349 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.