DPCstruct | MC39498

Metacluster Properties and Pfam Annotations

Number of structural domains1392
Mean domain length (aa)187 ± 31 aa
Standard deviation of domain lengths30.92
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.51
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.27
Pfam Score76.33
Assigned Pfam label(s) PF07833- PF04526- PF00223- CL0559- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D8GCS3 2-225 None
A0A3C1HFC6 19-239 None
A0A6H5I4A8 657-834 None
A0A7S4PT95 359-526 None
A0A1H9FRK5 21-191 None
A0A7S0G841 6-164 None
A0A1Z9KLU2 450-694 None
E4YQB0 11-148 None
A0A151F3G5 17-213 None
A0A151ELC1 333-483 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.