DPCstruct | MC39498

Metacluster Properties and Pfam Annotations

Number of structural domains1392
Mean domain length (aa)187 ± 31 aa
Standard deviation of domain lengths30.92
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.51
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.27
Pfam Score76.33
Assigned Pfam label(s) PF07833- PF04526- PF00223- CL0559- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E4PMC5 225-395 None
A0A661WV85 777-961 None
A0A842YYN6 2-183 None
A0A2V8ZRY1 164-332 None
I6ZYA3 16-214 None
A0A0G4N0E4 23-216 None
A0A2E2VW90 23-229 None
A0A2J6THS8 2-146 None
T1JT06 281-462 None
A0A6F9CAZ0 121-297 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.