DPCstruct | MC39498

Metacluster Properties and Pfam Annotations

Number of structural domains1392
Mean domain length (aa)187 ± 31 aa
Standard deviation of domain lengths30.92
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.51
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.27
Pfam Score76.33
Assigned Pfam label(s) PF07833- PF04526- PF00223- CL0559- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1M7PYT4 285-469 None
A0A6I4PVK7 556-768 None
A0A3M2CY67 139-305 None
A0A5C5G069 18-249 None
A0A2E3YH70 172-378 None
A0A7V1Z989 259-501 None
A0A512J7Z3 3-159 None
B3QWC6 687-852 None
A0A821BN26 11-161 None
R6U6G5 28-268 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.