DPCstruct | MC39498

Metacluster Properties and Pfam Annotations

Number of structural domains1392
Mean domain length (aa)187 ± 31 aa
Standard deviation of domain lengths30.92
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.51
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.27
Pfam Score76.33
Assigned Pfam label(s) PF07833- PF04526- PF00223- CL0559- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0F9K7Y3 10-199 EIDSEFGEPPIIDGYIDPSVQEWNEAIKNQAYIDDLPIELWVMQTAQNLYISIQLDLLPIARNSSEFIGLIISNSSSENIDDFIDAK…
A0A7C2YXD4 6-173 AERGLFDLLRYAVYDADDRWQLAFEFPTLPNAWNGPQGFSHPILYLYFDVGPGGSTAAHEEGKAAQVAFSPDRPWDYFVKVAGWPAY…
A0A226EK45 186-325 None
A0A239JI75 1-203 None
A0A3M1E340 283-493 None
A0A1G3LGE0 786-969 None
A0A7C1HVA8 25-240 None
A0A7R9A7P0 318-489 None
A0A1W9N9I6 56-278 None
A0A1H1VVW6 115-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.