DPCstruct | MC39472

Metacluster Properties and Pfam Annotations

Number of structural domains2
Mean domain length (aa)295 ± 18 aa
Standard deviation of domain lengths18.00
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score62.90
Mean fraction of residues predicted as intrinsically disordered0.51
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)42.35
Pfam Score83.33
Assigned Pfam label(s) PF04902- CL0003- PF04905

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A498LRB0 63-375 LPRSLGELQLYRILQKANLLCYYEAFIQQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKALRDWVTNPSIFNQPLTSLPV…
S4RQC0 7-283 QEEFLEIMALVGMASKPLHVRRLQKALQEWVNNPSVFSQVLPAFACASIPISKISNITTATATEGLNLGPKQATTGSASAGASTRVV…

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.