DPCstruct | MC39468

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)172 ± 23 aa
Standard deviation of domain lengths22.85
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.45
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)22.45
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S4RNY4 9-193 TEHCILPVSAESQPLFPAKMVSRLMQWTASTYDEYKVLPYTRPVVEAGLAQESDLYFSALIERGTAKLRVAVLLSPSFPSPAPILSL…
A0A0S7LHR0 2-131 AVVERGTARLHAAVVLSPRYPEVSPLFSLSLNWKGECSGRSDDNLRAVESEVNVFKNELQGPKPGHQLLTNQIARLCVCLDVYLETE…
A0A0C2J6X4 350-532 None
A0A7R9AWM5 465-654 None
A0A7D9MER1 2-179 None
D8LF18 501-737 None
V5H8E4 149-332 None
W2SZU4 319-488 None
A0A0B2W5M6 1-139 None
A0A7S0MXK4 3-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.