DPCstruct | MC3946

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)135 ± 17 aa
Standard deviation of domain lengths17.23
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.86
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)31.93
Pfam Score100.00
Assigned Pfam label(s) PF12237

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P4XQA6 99-229 None
A0A812M1Z4 138-270 None
A0A1Y5ID32 166-292 None
A0A7S4QZE8 489-624 None
A0A1V9XKS3 469-591 None
A0A835YQ92 192-328 None
A0A0S7GE34 100-260 None
A0A0S7GGU0 408-532 None
A0A2R5FYX9 399-549 None
E9HCG4 4-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.