DPCstruct | MC3946

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)135 ± 17 aa
Standard deviation of domain lengths17.23
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.86
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)31.93
Pfam Score100.00
Assigned Pfam label(s) PF12237

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S3X396 10-152 GGGGGVKRSRRGSVKAASSVVLTRGLAPGMVRLACGETHVSVSEAHLGKLWALYARSRPSPMPPAAAERFPEVAFCVVARQLSLQGG…
A0A0S7GJ11 148-274 PTPALPRVELHFENDVACLRFRGEMVKVNRGHFSKLELLYRYSCIDDPRFEKFLARVWCLLKRYQVMFGSGANEGSGLQGALPVAVF…
A0A2E0ILZ5 65-183 None
A0A7S1FGF8 62-187 None
A0A034V903 233-394 None
A0A5J4YXS3 147-267 None
T1PL29 33-188 None
C1MLJ5 194-335 None
A0A1S3IWL0 217-356 None
D2V319 489-624 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.