DPCstruct | MC39447

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)109 ± 10 aa
Standard deviation of domain lengths9.84
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score79.47
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)41.97
Pfam Score89.29
Assigned Pfam label(s) CL0279- PF04557

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S4R871 2-105 ALEYLKSHPLEPLAVEEFERACGVGIVVTPEQIEETVEGVIKKYKSQLLEERYHFNMGLIMAETRGLLKWADGKILKNEVDVQVLNM…
R7Q4E0 126-215 ERVTIDQSEFEEAAGVGVVVTEEEITAAVDSAIQENTPALVEKRYRFNTGLMQRDIMKNLRFAEGKAVSALITEKVAALLGPKTEAD…
A0A0N4WJU0 106-212 None
A0A2P6S9V4 1-91 None
A0A1A9UP05 5-112 None
A0A4Y7JEI4 281-387 None
A0A287KCS4 174-285 None
A0A1R3HRM5 94-200 None
A0A453E7S8 184-295 None
J9EQJ6 13-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.