DPCstruct | MC39405

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)167 ± 34 aa
Standard deviation of domain lengths34.44
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.38
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.56
Pfam Score92.52
Assigned Pfam label(s) CL0023- CL0125- PF01576- CL0072- PF00773

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A225WB75 39-256 None
A0A6V7UXY1 55-219 None
A0A0R3R3N7 14-140 None
B0XL38 77-276 None
A0A315VM04 164-305 None
A0A2R5GHD1 259-459 None
A0A2R5GC60 7-239 None
A0A7R8WDA0 329-479 None
A0A6A2WTZ6 263-464 None
A0A553Q121 13-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.